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Multicenter Study
. 2016 Mar;25(1):55-67.
doi: 10.1002/mpr.1487. Epub 2015 Aug 18.

Treatment patterns in inpatient depression care

Alessa von Wolff  1 , Ramona Meister  1 , Martin Härter  1 , Levente Kriston  1
Affiliations
Multicenter Study

Treatment patterns in inpatient depression care

Alessa von Wolff et al. Int J Methods Psychiatr Res. 2016 Mar.

Abstract

This study aimed to identify latent patterns of treatment combinations in inpatient depression care. A secondary analysis of routinely collected data on inpatient depression treatment from 2133 patients was conducted. Exploratory latent class modeling was used to identify distinct classes of treatment combinations based on antidepressant medication, psychotherapeutic interventions, and additional treatments. The classes were compared with regard to patient characteristics and treatment outcomes. Eight different classes of inpatient treatment combinations could be identified: 22.8% of the patients were treated with a combination labelled "standard modern antidepressants", 14.6% with "standard tricyclic antidepressants", 12.2% with "high intensity innovative strategies", 12.1% with "standard selective-reuptake-inhibitors", and 11.6% with "low intensity", 9.6% with "somatic", 8.8% with "high intensity traditional", and 8.3% with "high intensity psychosocial" care, respectively. Patients treated with different patterns of interventions differed statistically significantly regarding demographic and clinical characteristics. Responder rates ranged from 68.4% to 86.6% across treatment classes. The presented attempt of empirical modeling of a complex multifactorial intervention by means of latent class analysis proved to be a promising way of capturing the complexity of routine inpatient depression treatment. The identified classes of treatment combinations may provide relevant information for a re-evaluation and improvement of inpatient depression treatment strategies.

Keywords: complex interventions; depressive disorders; health services; inpatient treatment; latent class analysis.

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References

    1. American Psychiatric Association (1994) Global Assessment of Functiong (GAF) scale In Diagnostic and Statistical Manual for Mental Disorders (4th Edition) (DSM‐IV), pp. 758–759, Washington, DC: American Psychoatric Association.
    1. American Psychiatric Association (2010) Practice Guideline for the Treatment of Patients with Major Depressive Disorder, Third Edition. http://psychiatryonline.org/guidelines [accessed June 8, 2015].
    1. Barbui C., Ciuna A., Nosè M., Levi D., Andretta M., Patten S.B., Amaddeo F., Tansella M. (2005) Drug treatment modalities in psychiatric inpatient practice. A 20‐year comparison. European Archives of Psychiatry and Clinical Neuroscience, 255(2), 136–142. - PubMed
    1. Bauer D., Curran P. (2003) Distributional assumptions of growth mixture models: implications for overextraction of latent trajectory classes. Psychological Methods, 8(3), 338–363. - PubMed
    1. Bauer M., Monz B.U., Montejo A.L., Quail D., Dantchev N., Demyttenaere K., Garcia‐Cebrian A., Grassi L., Perahia D.G., Reed C., Tylee A. (2008) Prescribing patterns of antidepressants in Europe: results from the factors influencing depression endpoints research (FINDER) study. European Psychiatry, 23(1), 66–73. - PubMed

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