Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Jul-Aug;60(4):420.
doi: 10.4103/0019-5154.160515.

Solitary Ulcerated Congenital Giant Juvenile Xanthogranuloma

Su Yuen Ng  1
Affiliations

Solitary Ulcerated Congenital Giant Juvenile Xanthogranuloma

Su Yuen Ng. Indian J Dermatol. 2015 Jul-Aug.

Abstract

A 3-month-old female patient with a giant ulcerated nodule over the back since birth was diagnosed as congenital giant juvenile xanthogranuloma (JXG) based on clinical and histopathological examination. Congenital giant JXG with ulceration at birth is a rare presentation of JXG and commonly misdiagnosed. This case emphasizes the importance of being aware of the myriad presentations of JXG in order to make a correct diagnosis and avoid unnecessary investigations or treatment.

Keywords: Hemangioma; juvenile xanthogranuloma; ulcerated.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: Nil.

Figures

Figure 1
Figure 1
Ulcerated nodule over back of the patient at 3 months of age
Figure 2
Figure 2
Histopathological examination of skin biopsy showing dense dermal infiltrate of foamy histiocytes, foreign body and touton giant cells (black arrow). H and E, ×100 (a), H and E, ×400 (b)
Figure 3
Figure 3
Hyperpigmented atrophic plaque over back of the patient at 9 months of age
See this image and copyright information in PMC

References

    1. Chang MW. Update on juvenile xanthogranuloma: Unusual cutaneous and systemic variants. Semin Cutan Med Surg. 1999;18:195–205. - PubMed
    1. Ceyhan AM, Aynali G, Chen W, Kapucuoglu N. Congenital giant juvenile xanthogranuloma initially masquerading as hemangioma. Eur J Dermatol. 2011;21:431–3. - PubMed
    1. Imiela A, Carpentier O, Segard-Drouard M, Martin de Lassalle E, Piette F. Juvenile xanthogranuloma: A congenital giant form leading to a wide atrophic sequela. Pediatr Dermatol. 2004;21:121–3. - PubMed
    1. Clayton TH, Holder JE, Clark SM. Solitary giant juvenile xanthogranuloma presenting in a neonate. Br J Dermatol. 2004;15(1Suppl 68):67–79.
    1. Yazganoglu KD, Erdem Y, Buyukbabani N, Baykal C. A giant congenital plaque. Pediatr Dermatol. 2012;29:217–8. - PubMed

LinkOut - more resources