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. 2015 Jun 9;2(7):621-2.
doi: 10.1016/j.ebiom.2015.06.002. eCollection 2015 Jul.

Can we be SMaRT-er in our approach to cancer therapy?

Affiliations

Can we be SMaRT-er in our approach to cancer therapy?

Christina Gruber et al. EBioMedicine. .
No abstract available

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References

    1. Chao H., Mansfield S.G., Bartel R.C. Phenotype correction of hemophilia A mice by spliceosome-mediated RNA trans-splicing. Nat. Med. 2003;9:1015–1019. - PubMed
    1. Gruber C., Koller U., Murauer E.M. The design and optimization of RNA trans-splicing molecules for skin cancer therapy. Mol. Oncol. 2013;7:1056–1068. - PMC - PubMed
    1. He X., Liu F., Yan J. Trans-splicing repair of mutant p53 suppresses the growth of hepatocellular carcinoma cells in vitro and in vivo. Sci. Rep. 2015;5:8705. - PMC - PubMed
    1. Koller U., Hainzl S., Kocher T. Trans-splicing improvement by the combined application of antisense strategies. Int. J. Mol. Sci. 2015;16:1179–1191. - PMC - PubMed
    1. Monjaret F., Bourg N., Suel L. Cis-splicing and translation of the pre-trans-splicing molecule combine with efficiency in spliceosome-mediated RNA trans-splicing. Mol. Ther. 2014;22:1176–1187. - PMC - PubMed

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