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. 2015 Dec;100(12):e515-8.
doi: 10.3324/haematol.2015.126763. Epub 2015 Aug 20.

Clinical profile associated with infections in patients with chronic lymphocytic leukemia. Protective role of immunoglobulin replacement therapy

Andrea Visentin  1 , Nicolò Compagno  1 , Francesco Cinetto  1 , Silvia Imbergamo  2 , Renato Zambello  1 , Francesco Piazza  1 , Gianpietro Semenzato  1 , Livio Trentin  3 , Carlo Agostini  3
Affiliations

Clinical profile associated with infections in patients with chronic lymphocytic leukemia. Protective role of immunoglobulin replacement therapy

Andrea Visentin et al. Haematologica. 2015 Dec.
No abstract available

Keywords: CLL; hypogammaglobulinemia; immunoglobulin replacement therapy; infections; secondary hypogammaglobulinemia.

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Figures

Figure 1.
Figure 1.
Comparison of Ig levels between patients with and without a history of infection and Kaplan-Meier curves estimate of time to major infection and overall survival. The upper panels compare (A) IgG, (B) IgA and (C) IgM between patients with (PwI) and without a history of major infection (PwoI) by the Mann-Whitney test. Panel (D) shows a histogram of the percentage of patients with and without combined antibody deficiency (CAD and non-CAD, respectively). Times to infection were estimated according to (E) previous need of treatment, (F) immunoglobulin deficiency and (G) combined analysis. (H) Overall survival was estimated according to immunoglobulin replacement therapy.
See this image and copyright information in PMC

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