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. 2015 Aug;28(3):175-80.
doi: 10.2337/diaspect.28.3.175.

Hypertension Management in Diabetic Kidney Disease

Vikram Patney  1 , Adam Whaley-Connell  2 , George Bakris  3
Affiliations

Hypertension Management in Diabetic Kidney Disease

Vikram Patney et al. Diabetes Spectr. 2015 Aug.

Abstract

IN BRIEF Hypertension is prevalent in most individuals with diabetic kidney disease (DKD). Failure to treat hypertension appropriately in this subgroup of patients results in an increased risk of cardiovascular morbidity and mortality, as well as a faster progression of kidney disease. The current guidance for appropriate treatment of hypertension in this high-risk population provides an opportunity to improve both kidney and cardiovascular outcomes. This review discusses the current state of evidence-based hypertension management in patients with DKD.

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Figures

FIGURE 1.
FIGURE 1.
An updated general approach for achieving BP goals in people with diabetes. This integrated approach summarizes the National Kidney Foundation consensus report and American Society of Hypertension guidelines (49,50). ACEI, ACE inhibitor; ARB, angiotensin receptor blocker; CCB, calcium channel blocker; K, potassium.*Diuretics such as chlorthalidone and indapamide. **Risk factors for hyperkalemia; note hyperkalemia is defined as serum potassium >5.5 mEq/L.
See this image and copyright information in PMC

References

    1. Burrows NR, Li Y, Geiss LS. Incidence of treatment for end-stage renal disease among individuals with diabetes in the U.S. continues to decline. Diabetes Care 2010;33:73–77 - PMC - PubMed
    1. Gregg EW, Li Y, Wang J, et al. . Changes in diabetes-related complications in the United States, 1990–2010. N Engl J Med 2014; 370:1514–1523 - PubMed
    1. U.K. Prospective Diabetes Study Group Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ 1998;317:703–713 - PMC - PubMed
    1. Brenner BM, Cooper ME, de Zeeuw D, et al. .; RENAAL Study Investigators . Effect of Losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001;345:861–869 - PubMed
    1. U.S. Renal Data System 2010 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in United States. Bethesda, Md, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2010. Available from http://www.usrds.org/atlas10.aspx. Accessed 14 May 2015