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. 2015 Dec;99(3):533-6.
doi: 10.1016/j.yexmp.2015.07.004. Epub 2015 Aug 21.

Finding mouse models of human lymphomas and leukemia's using the Jackson laboratory mouse tumor biology database

Dale A Begley  1 , John P Sundberg  2 , Debra M Krupke  2 , Steven B Neuhauser  2 , Carol J Bult  2 , Janan T Eppig  2 , Herbert C Morse 3rd  3 , Jerrold M Ward  4
Affiliations

Finding mouse models of human lymphomas and leukemia's using the Jackson laboratory mouse tumor biology database

Dale A Begley et al. Exp Mol Pathol. 2015 Dec.

Abstract

Many mouse models have been created to study hematopoietic cancer types. There are over thirty hematopoietic tumor types and subtypes, both human and mouse, with various origins, characteristics and clinical prognoses. Determining the specific type of hematopoietic lesion produced in a mouse model and identifying mouse models that correspond to the human subtypes of these lesions has been a continuing challenge for the scientific community. The Mouse Tumor Biology Database (MTB; http://tumor.informatics.jax.org) is designed to facilitate use of mouse models of human cancer by providing detailed histopathologic and molecular information on lymphoma subtypes, including expertly annotated, on line, whole slide scans, and providing a repository for storing information on and querying these data for specific lymphoma models.

Keywords: Digital slides; Leukemia; Lymphoma; Mice; Mouse tumor biology database; Virtual slides.

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Figures

Figure 1
Figure 1
Whole- Slide Scan image from MTB. This is a Pathology Image Detail for a lymphobastic lymphoma. The Link in the caption connects to a whole slide scan of the image.
See this image and copyright information in PMC

References

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