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. 2015 Aug 24;34(4):383-4.
doi: 10.1016/j.devcel.2015.08.002.

Making a Choice: How Cadherin Switching Controls Cell Migration

Rashmi Priya  1 , Alpha S Yap  2
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Making a Choice: How Cadherin Switching Controls Cell Migration

Rashmi Priya et al. Dev Cell. .
Free article

Abstract

Cells that undergo epithelial-to-mesenchymal transitions (EMTs) commonly switch from expressing E-cadherin to N-cadherin. But why this occurs is not well understood. In the current issue of Developmental Cell, Scarpa et al. (2015) identify a reason: cadherin switching controls Rac signaling to determine how cell locomotion is regulated by contact.

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