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. 2015 Dec;29(12):2418-21.
doi: 10.1038/leu.2015.238. Epub 2015 Aug 26.

Common genetic variants in 11q13.3 and 9q22.33 are associated with molecular subgroups of multiple myeloma

S W Erickson  1 , O W Stephens  2 , S S Chavan  2 , E Tian  2 , J Epstein  2 , B Barlogie  2 , C J Heuck  2 , A J Vangsted  3
Affiliations

Common genetic variants in 11q13.3 and 9q22.33 are associated with molecular subgroups of multiple myeloma

S W Erickson et al. Leukemia. 2015 Dec.
No abstract available

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Conflict of interest statement

Conflict-of-interest disclosure: The authors declare no conflict of interest.

Figures

Figure 1
Figure 1. Kaplan-Meier plot of overall survival for A: CCND1-hi patients by rs603965 genotype and B: PR subgroup patients by rs73486634 (FOXE1/XPA) genotype
See this image and copyright information in PMC

Comment on

  • Inherited genetic susceptibility to monoclonal gammopathy of unknown significance.
    Weinhold N, Johnson DC, Rawstron AC, Försti A, Doughty C, Vijayakrishnan J, Broderick P, Dahir NB, Begum DB, Hosking FJ, Yong K, Walker BA, Hoffmann P, Mühleisen TW, Langer C, Dörner E, Jöckel KH, Eisele L, Nöthen MM, Hose D, Davies FE, Goldschmidt H, Morgan GJ, Hemminki K, Houlston RS. Weinhold N, et al. Blood. 2014 Apr 17;123(16):2513-7; quiz 2593. doi: 10.1182/blood-2013-10-532283. Epub 2014 Jan 21. Blood. 2014. PMID: 24449210

References

    1. Weinhold N, Johnson DC, Rawstron AC, Forsti A, Doughty C, Vijayakrishnan J, et al. Inherited genetic susceptibility to monoclonal gammopathy of unknown significance. Blood. 2014 Apr 17;123(16):2513–7. - PubMed
    1. Zhan F, Huang Y, Colla S, Stewart JP, Hanamura I, Gupta S, et al. The molecular classification of multiple myeloma. Blood. 2006 Sep 15;108(6):2020–8. - PMC - PubMed
    1. Zhou Y, Zhang Q, Stephens O, Heuck CJ, Tian E, Sawyer JR, et al. Prediction of cytogenetic abnormalities with gene expression profiles. Blood. 2012 May 24;119(21):e148–e150. - PMC - PubMed
    1. Tian E, Sawyer JR, Heuck CJ, Zhang Q, van RF, Barlogie B, et al. In multiple myeloma, 14q32 translocations are nonrandom chromosomal fusions driving high expression levels of the respective partner genes. Genes Chromosomes Cancer. 2014 Jul;53(7):549–57. - PMC - PubMed
    1. Broderick P, Chubb D, Johnson DC, Weinhold N, Forsti A, Lloyd A, et al. Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk. Nat Genet. 2012 Jan;44(1):58–61. - PMC - PubMed

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