Metabolic Flexibility and Dysfunction in Cardiovascular Cells

Affiliations

¹ From the Division of Metabolism, Endocrinology and Nutrition, Departments of Medicine (S.N.V., K.E.B.) and Pathology (K.E.B.), Diabetes and Obesity Center of Excellence, University of Washington School of Medicine, Seattle.
² From the Division of Metabolism, Endocrinology and Nutrition, Departments of Medicine (S.N.V., K.E.B.) and Pathology (K.E.B.), Diabetes and Obesity Center of Excellence, University of Washington School of Medicine, Seattle. bornf@u.washington.edu.

Review

Sara N Vallerie et al. Arterioscler Thromb Vasc Biol. 2015 Sep.

. 2015 Sep;35(9):e37-42.

doi: 10.1161/ATVBAHA.115.306226.

¹ From the Division of Metabolism, Endocrinology and Nutrition, Departments of Medicine (S.N.V., K.E.B.) and Pathology (K.E.B.), Diabetes and Obesity Center of Excellence, University of Washington School of Medicine, Seattle.
² From the Division of Metabolism, Endocrinology and Nutrition, Departments of Medicine (S.N.V., K.E.B.) and Pathology (K.E.B.), Diabetes and Obesity Center of Excellence, University of Washington School of Medicine, Seattle. bornf@u.washington.edu.

No abstract available

Keywords: cardiac myocyte; endothelial cells; fatty acids; glycolysis; macrophages; metabolic syndrome; metabolism.

References

1. Galvan-Pena S, O’Neill LA. Metabolic reprograming in macrophage polarization. Front Immunol. 2014;5:420. - PMC - PubMed
1. Eelen G, de Zeeuw P, Simons M, Carmeliet P. Endothelial cell metabolism in normal and diseased vasculature. Circ Res. 2015;116:1231–1244. - PMC - PubMed
1. Kolwicz SC, Jr, Purohit S, Tian R. Cardiac metabolism and its interactions with contraction, growth, and survival of cardiomyocytes. Circ Res. 2013;113:603–616. - PMC - PubMed
1. Muoio DM, Newgard CB. Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes. Nat Rev Mol Cell Biol. 2008;9:193–205. - PubMed
1. Samuel VT, Shulman GI. Mechanisms for insulin resistance: Common threads and missing links. Cell. 2012;148:852–871. - PMC - PubMed