Performance of Xpert MTB/RIF Assay in Diagnosis of Pleural Tuberculosis by Use of Pleural Fluid Samples
- PMID: 26311855
- PMCID: PMC4609697
- DOI: 10.1128/JCM.02182-15
Performance of Xpert MTB/RIF Assay in Diagnosis of Pleural Tuberculosis by Use of Pleural Fluid Samples
Abstract
Prospectively, 162 pleural fluid samples from patients with probable tuberculous pleural effusion were tested by the Xpert MTB/RIF assay and the Bactec MGIT-960 culture system. Of these, 43 (26.5%) were positive in the MGIT-960 culture, and 23 (14.2%), in the Xpert MTB/RIF assay. The sensitivity and specificity of the Xpert MTB/RIF compared with the MGIT-960 culture were 54.8% and 100%, respectively.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.
Figures
References
-
- WHO. 2014. Global tuberculosis report. http://apps.who.int/iris/bitstream/10665/137094/1/9789241564809_eng.pdf?....
-
- Tortoli E, Russo C, Piersimoni C, Mazzola E, Dal Monte P, Pascarella M, Borroni E, Mondo A, Piana F, Scarparo C, Coltella L, Lombardi G, Cirillo DM. 2012. Clinical validation of Xpert MTB/RIF for the diagnosis of extrapulmonary tuberculosis. Eur Respir J 40:442–447. doi:10.1183/09031936.00176311. - DOI - PubMed
-
- Meldau R, Peter J, Theron G, Calligaro G, Allwood B, Symons G, Khalfey H, Ntombenhle G, Govender U, Binder A, Zyl-Smit R van, Dheda K. 2014. Comparison of same day diagnostic tools, including Gene Xpert and unstimulated IFN-γ for the evaluation of pleural tuberculosis: a prospective cohort study. BMC Pulm Med 14:58. doi:10.1186/1471-2466-14-58. - DOI - PMC - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources