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Case Reports
. 2015 Jul-Sep;6(3):166-8.
doi: 10.4103/0976-500X.162009.

Nebivolol-induced gynecomastia

Erkan Köklü  1 , Şakir Arslan  1 , İsa Öner Yüksel  1 , Nermin Bayar  1 , Deniz Demirci  1
Affiliations
Case Reports

Nebivolol-induced gynecomastia

Erkan Köklü et al. J Pharmacol Pharmacother. 2015 Jul-Sep.

Abstract

Adverse drug reactions play a substantial role in the etiology of gynecomastia. Gynecomastia as an adverse drug reaction, related to some cardiovascular drugs, has been reported in literature. Nebivolol is a third generation beta-blocker, and gynecomastia as an adverse effect on the consumption of this drug has not been reported in any article yet. We herein present the case of a 42-year-old male, who developed bilateral gynecomastia following nebivolol use and complete regression after discontinuation of nebivolol. Other reasons causing gynecomastia were excluded. Discontinuation of the responsible drug is quite sufficient with regard to the treatment of drug-induced gynecomastia, without any pharmacological or surgical treatment.

Keywords: Antihypertensive therapy; drug-induced gynecomastia; nebivolol.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Bilateral gynecomastia
Figure 2
Figure 2
Bilateral gynecomastia
Figure 3
Figure 3
Bilateral glandular tissue growth in the retroareolar region of the breast demonstrated in mammography
See this image and copyright information in PMC

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