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Case Reports
. 2015 May-Jun;90(3 Suppl 1):77-80.
doi: 10.1590/abd1806-4841.20153624.

Possibly drug-induced palpable migratory arciform erythema

Fernando Luiz Teixeira Dantas  1 , Neusa Yuriko Sakai Valente  1 , Isis Suga Veronez  1 , Priscila Kakizaki  1 , Juliana Ribeiro Leitão  1 , Rafael Cavanellas Fraga  1
Affiliations
Case Reports

Possibly drug-induced palpable migratory arciform erythema

Fernando Luiz Teixeira Dantas et al. An Bras Dermatol. 2015 May-Jun.

Abstract

Palpable migratory arciform erythema is an entity of unknown etiology, with few published cases in the literature. The clinical and histopathological features of this disease are difficult to be distinguished from those of Jessner's lymphocytic infiltration of the skin, lupus erythematous tumidus and the deep erythema annulare centrifugum. We describe here the first two Brazilian cases of palpable migratory arciform erythema. The patients presented with infiltrated annular plaques and erythematous arcs without scales. These showed centrifugal growth before disappearing without scarring or residual lesions after a few days. They had a chronic course with repeated episodes for years. In addition, these cases provide evidence of a drug-induced etiology.

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Conflict of interest statement

Conflict of Interest: None.

Figures

FIGURE 1
FIGURE 1
case 1 - lesion on the left arm. Arciform, elevated, infiltrated and erythematous plaque with mild erythema in the central area and 8 cm in diameter
FIGURE 2
FIGURE 2
Histopathology of case 1 - hematoxylin-eosin, 400x magnification. Detail of a predominantly lymphocytic, mixed infiltrate with neutrophils and eosinophils in the periadnexal fat
FIGURE 3
FIGURE 3
case 1 - acral lesions. Arciform, palpable, erythematous plaques in the hypothenar region of the hand, on the heel and lateral border of the foot
FIGURE 4
FIGURE 4
case 2 - lesion on the right arm. Annular, erythematous, infiltrated and palpable plaques with spared center on the lateral region of the arm
FIGURE 5
FIGURE 5
Histopathology of case 2 - hematoxylin-eosin, 100x magnifi cation. Mildly acanthotic epidermis. Dermis with perivascular lymphocytic infiltrate and moderate interstitial mucinosis
FIGURE 6
FIGURE 6
Histopathology of case 2 - OM x 200. Alcian blue staining counter-stained with PAS show moderate interstitial mucin deposition in the reticular dermis
See this image and copyright information in PMC

References

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