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Case Reports
. 2015 May-Jun;90(3 Suppl 1):130-3.
doi: 10.1590/abd1806-4841.20153798.

Frontal cutaneous meningioma--Case report

Leonor Ramos  1 , Ines Coutinho  1 , José Carlos Cardoso  1 , Helena Garcia  1 , Margarida Robalo Cordeiro  1
Affiliations
Case Reports

Frontal cutaneous meningioma--Case report

Leonor Ramos et al. An Bras Dermatol. 2015 May-Jun.

Abstract

Cutaneous meningiomas are rare tumors most commonly located on the scalp. We report the case of a 55-year-old male who presented with a 2 x 3 cm tumoral lesion on the forehead. The lesion was hard, adherent and covered by normal skin. Incisional biopsy revealed a proliferation of monomorphic round cells, organized in nests and focally forming pseudovascular spaces. Immunohistochemical study revealed positivity for epithelial antigen membrane and vimentin. Vascular markers, cytokeratins and S100 protein were negative. A brain CT scan did not show any evidence of intracranial meningioma. The authors describe the case of a cutaneous frontal meningioma in probable relation with previous cranioencephalic trauma.

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Conflict of interest statement

Conflict of Interest: None.

Figures

FIGURE 1
FIGURE 1
2x3 cm, firm, ovoid subcutaneous mass, adherent to the deep tissues and covered by normal skin in the frontal region
FIGURE 2
FIGURE 2
Histopathology of the lesion (HE stain) A. Proliferation of cells in lobular arrangement between adipose and muscular tissue. B. Proliferation of cells arranged in nests and lobules. C. Some areas presented intersticial growth, with collagen dissection, evoking the formation of vascular spaces. Areas of entrapment of hyaline collagen, forming rounded collagen bodies. D. The cells of the proliferation were round, monomorphic, without mitosis or significant atypia
FIGURE 3
FIGURE 3
Immunohistochemical staining revealed positivity for vimentin (A) and EMA (B)
FIGURE 4
FIGURE 4
Cranioencephalic CT revealed frontal mass and a bony defect in the frontal bone (*). There were no intracranial masses detected. Frontal e n c e p h a l o m a l a - cia and ventricular asymmetry had been already present in previous exams
See this image and copyright information in PMC

References

    1. Miedema JR, Zedek D. Cutaneous meningioma. Arch Pathol Lab Med. 2012;136:208–211. - PubMed
    1. Lopez DA, Silvers DN, Helwig EB. Cutaneous meningiomas - a clinicopathologic study. Cancer. 1974;34:728–744. - PubMed
    1. Borggreven PA, de Graaf FH, van der Valk P, Leemans CR. Post-traumatic cutaneous meningioma. J Laryngol Otol. 2004;118:228–230. - PubMed
    1. Hussein MR, Abdelwahed AR. Primary cutaneous meningioma of the scalp: a case report and review of literature. J Cutan Pathol. 2007;34:26–28. - PubMed
    1. Campbell BA, Jhamb A, Maguire JA, Toyota B, Ma R. Meningiomas in 2009: controversies and challenges. Am J Clin Oncol. 2009;32:73–85. - PubMed

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