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Case Reports
. 2015 May-Jun;90(3 Suppl 1):147-9.
doi: 10.1590/abd1806-4841.20153450.

Follicular mucinosis: an important differential diagnosis of leprosy in an endemic area

Danielle Cristine Westphal  1 , Silmara Navarro Pennini  1 , Petra Pereira de Souza  1 , Gustavo Ávila Maquiné  2 , Antônio Pedro Mendes Schettini  1 , Mônica Santos  1
Affiliations
Case Reports

Follicular mucinosis: an important differential diagnosis of leprosy in an endemic area

Danielle Cristine Westphal et al. An Bras Dermatol. 2015 May-Jun.

Abstract

Primary follicular mucinosis is a rare dermatosis characterized by the accumulation of mucin in the follicular epithelium and sebaceous glands. Clinically, it is characterized by the presence of papules or well-circumscribed and infiltrated plaques. In this paper, we report the case of a female patient, seven years old, evolving for three months with an asymptomatic, erythematous and infiltrated plaque located in the chin region. The research of thermal, pain and tactile sensitivity was inconclusive. Histological findings confirmed the diagnosis of follicular mucinosis. There was regression of the lesion with the use of medium potency topical corticosteroids for 20 days. The pathogenesis of follicular mucinosis remains unknown, being in some cases associated with lymphoproliferative disorders. In endemic areas of leprosy, isolated and infiltrated follicular mucinosis lesions should be further differentiated from leprosy.

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Conflict of interest statement

Conflict of Interest: None.

Figures

FIGURE 1
FIGURE 1
Erythematous-brownish oval-shaped plaque, well-circumscribed and infiltrated, measuring approximately 2.5 cm at its largest diameter, located in the chin region
FIGURE 2
FIGURE 2
In hematoxilin-eosin staining, reticular degeneration in the infundibulum of hair follicles was observed, forming large clear spaces, with lymphohistiocytic infiltrate around vessels and appendages and discrete collagen fibrosis
FIGURE 3
FIGURE 3
Complete remission of lesion after treatment with topical corticoid
See this image and copyright information in PMC

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