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Case Reports
. 2015 May-Jun;90(3 Suppl 1):223-5.
doi: 10.1590/abd1806-4841.20153840.

Laugier-Hunziker syndrome--Case report

Jovan Lalosevic  1 , Dubravka Zivanovic  1 , Dusan Skiljevic  1 , Ljiljana Medenica  1
Affiliations
Case Reports

Laugier-Hunziker syndrome--Case report

Jovan Lalosevic et al. An Bras Dermatol. 2015 May-Jun.

Abstract

Laugier-Hunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. We present the case of a 63-year-old female with progressive, asymptomatic hyperpigmentation of buccal mucosa and a 7-year history of hyperpigmentation in several fingernails. Laugier-Hunziker syndrome was diagnosed based on the clinical features presented, dermoscopic findings and exclusion of underlying systemic diseases. Laugier-Hunziker syndrome is regarded as a diagnosis of exclusion. By identifying Laugier-Hunziker syndrome, other, more severe syndromes associated with hyperpigmentations can be excluded, namely Addison's disease and Peutz-Jeghers syndrome.

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Conflict of interest statement

Conflict of interest: None.

Figures

FIGURE 1
FIGURE 1
A e B. Regular, brownish reticular pattern on the buccal mucosa
FIGURE 2
FIGURE 2
A. Homogenous and band-like hyperpigmentation on the patient’s fingernails, B. Longitudinal hyperpigmentation on both first toenails and homogenous pigmentation on all other toenails
FIGURE 3
FIGURE 3
Pseudo-Hutchinson’s sign, with homogeneous, brownish and grayish longitudinal bands and lines with ill-defined margins on the nail plate
See this image and copyright information in PMC

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