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Case Reports
. 2015 May-Jun;90(3 Suppl 1):229-31.
doi: 10.1590/abd1806-4841.20153685.

Stewart Treves Syndrome

Elisangela Samartin Pegas Pereira  1 , Elisa Trino de Moraes  1 , Daniela Melo Siqueira  1 , Marcel Alex Soares dos Santos  1
Affiliations
Case Reports

Stewart Treves Syndrome

Elisangela Samartin Pegas Pereira et al. An Bras Dermatol. 2015 May-Jun.

Abstract

Stewart-Treves Syndrome is characterized by the presence of lymphangiosarcoma on limb extremities. Rare, it occurs in 0.5% of patients who have undergone radical mastectomy with axillary node dissection. The main cause is chronic lymphedema with endothelial and lymphatic differentiation, with no direct relationship to breast cancer. Seven years after a radical right-side mastectomy with lymph node dissection and adjuvant therapy, the patient developed a lesion on her right arm. The dermatological examination revealed an erythematous nodule with bleeding surface on chronic right forearm lymphedema. After the biopsy, a lymphangiosarcoma on chronic lymphedema was diagnosed. Infrequent, this syndrome is relevant because of its associated mortality. Early diagnosis is important to improve survival and reduce complications.

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Conflict of interest statement

Conflict of Interest: None.

Figures

FIGURE 1
FIGURE 1
Multiple papules and erythematous-violet nodules on chronic lymphedema in the right upper limb
FIGURE 2
FIGURE 2
Local recurrence of lesions in the base of the amputated arm
FIGURE 3
FIGURE 3
Irregular vascular spaces of different sizes and covered by polygonal cells with hyperchromatic pleomorphic nuclei (hematoxylineosin 10X).
See this image and copyright information in PMC

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