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Review
. 2015 Sep;44(3):661-6.
doi: 10.1016/j.gtc.2015.05.007. Epub 2015 Jun 19.

Rationale for a Helicobacter pylori Test and Treatment Strategy in Gastroesophageal Reflux Disease

Affiliations
Review

Rationale for a Helicobacter pylori Test and Treatment Strategy in Gastroesophageal Reflux Disease

Nimish Vakil. Gastroenterol Clin North Am. 2015 Sep.

Abstract

Conflicting data have been published on the effect of long-term proton pump inhibitor therapy on the gastric mucosa in Helicobacter pylori-infected subjects. In this article, the available data are reviewed and a rationale is offered for why infected patients who are about to commence long-term proton pump inhibitor therapy should be offered eradication therapy.

Keywords: GERD; Gastric atrophy; H pylori; Intestinal metaplasia; Proton pump inhibitors.

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