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Review
. 2015 Sep;44(3):587-602.
doi: 10.1016/j.ecl.2015.05.007. Epub 2015 Jun 23.

The Effect of Menopausal Hormone Therapies on Breast Cancer: Avoiding the Risk

Valerie A Flores  1 , Hugh S Taylor  2
Affiliations
Review

The Effect of Menopausal Hormone Therapies on Breast Cancer: Avoiding the Risk

Valerie A Flores et al. Endocrinol Metab Clin North Am. 2015 Sep.

Abstract

Estrogen and P treatment results in greater risk of breast cancer than placebo. Treatment with estrogen alone does not increase the risk of breast cancer, may be used by women who have had a hysterectomy, and may even result in a decreased risk of breast cancer. Continued research seeks to improve the understanding of the interplay between estrogen and progestogens that predispose to adverse effects on breast tissue. Caution over this hypothesized benefit is warranted until it is substantiated by data on the incidence of breast cancer in tissue selective estrogen complex users.

Keywords: Breast cancer; Estrogens; Hormone therapy; Menopause; Progestogen.

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