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Case Reports
. 2015 Jun;7(2):155-8.
doi: 10.4274/jcrpe.1740.

Dermal and Ophthalmic Findings in Pseudohypoaldosteronism

Sabriye Korkut  1 , Emir Gökalp, Ahmet Özdemir, Selim Kurtoğlu, Şafak Demirtaş, Ülkü Gül, Osman Baştuğ
Affiliations
Case Reports

Dermal and Ophthalmic Findings in Pseudohypoaldosteronism

Sabriye Korkut et al. J Clin Res Pediatr Endocrinol. 2015 Jun.

Abstract

Pseudohypoaldosteronism (PHA) is defined as a state of resistance to aldosterone, a hormone crucial for electrolyte equilibrium. The genetically transmitted type of PHA is primary hypoaldosteronism. Secondary hypoaldosteronism develops as a result of hydronephrosis or hydroureter. PHA patients suffer from severe hyponatremia and a severe clinical condition due to severe loss of salt can be encountered in the neonatal period. Dermal findings in the form of miliaria rubra can also develop in these patients. With the loss of salt, abnormal accumulation of sebum in the eye due to a defect in the sodium channels can also occur. In this paper, a case of PHA in a newborn showing typical dermatological and ophthalmological findings is presented.

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Figures

Figure 1
Figure 1. The appearance of the miliaria rubra on the trunk and arm.
Figure 2
Figure 2. The appearance of salt crystals at the base of the follicles of the face.
Figure 3
Figure 3. Presence of a white opaque discharge with an appearance of a row of teeth at the bottom of the eyelashes.
See this image and copyright information in PMC

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