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Review
. 2013:2013:378790.
doi: 10.1155/2013/378790. Epub 2013 Dec 17.

Markers of Oxidative Stress during Diabetes Mellitus

Brahm Kumar Tiwari  1 , Kanti Bhooshan Pandey  2 , A B Abidi  1 , Syed Ibrahim Rizvi  3
Affiliations
Review

Markers of Oxidative Stress during Diabetes Mellitus

Brahm Kumar Tiwari et al. J Biomark. 2013.

Abstract

The prevalence of diabetes mellitus is rising all over the world. Uncontrolled state of hyperglycemia due to defects in insulin secretion/action leads to a variety of complications including peripheral vascular diseases, nephropathy, neuropathy, retinopathy, morbidity, and/or mortality. Large body of evidence suggests major role of reactive oxygen species/oxidative stress in development and progression of diabetic complications. In the present paper, we have discussed the recent researches on the biomarkers of oxidative stress during type 2 diabetes mellitus.

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Figures

Figure 1
Figure 1
Schematic representation of the status of oxidative stress markers during diabetes. MDA: malondialdehyde, AOPP: Advanced oxidation protein products, PCO: protein carbonyls, GSH: reduced glutathione, and SOD: superoxide dismutase.
See this image and copyright information in PMC

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