Recent Advances in the Selective Oxidation of Alkyl C-H Bonds Catalyzed by Iron Coordination Complexes

Abstract

Selective and stereoretentive oxidation of alkyl C-H bonds has been described over the last decade by employing biologically inspired iron coordination complexes as catalysts and hydrogen peroxide as oxidant. Examples of catalyst dependent C-H site selectivity have started to appear. The current paper describes an account of these findings.

Keywords: Alkyl C–H oxidation; Aminopyridine ligands; Bioinspired catalysis; Hydrogen peroxide; Iron coordination complexes; Nonheme oxygenases; Selectivity.