Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Sep;36(9):1033-8.
doi: 10.15537/smj.2015.9.12270.

Pemphigus and pregnancy. Analysis and summary of case reports over 49 years

Lin Lin  1 , Xin Zeng, Qianming Chen
Affiliations
Review

Pemphigus and pregnancy. Analysis and summary of case reports over 49 years

Lin Lin et al. Saudi Med J. 2015 Sep.

Abstract

Pemphigus is a group of immune-mediated bullous disorders, which often cause fragile blisters and extensive lesions of the skin or mucous membranes, such as in the mouth. This disease could be life-threatening in some cases. During pregnancy, its condition will become more complicated due to the change in the mother's hormone level and the effect of drug therapy on both the mother and her fetus. Thus, it will be more difficult to identify the clinical manifestations and to establish the treatment plan. In this article, we present a comprehensive review of pemphigus and pregnancy by analyzing 47 cases of pemphigus reported between 1966 and 2014, with diagnosis before or during pregnancy. The aim of this study is to make a comprehensive review of pemphigus and pregnancy, provide organized and reliable information for obstetricians, dermatologists, physicians, and oral medicine specialists.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Regional distribution of 47 cases of pemphigus and pregnancy between 1966 and 2014.
See this image and copyright information in PMC

References

    1. Kitajima Y, Aoyama Y. A perspective of pemphigus from bedside and laboratory-bench. Clin Rev Allergy Immunol. 2007;33:57–66. - PubMed
    1. Ruocco E, Wolf R, Ruocco V, Brunetti G, Romano F, Lo Schiavo A. Pemphigus: associations and management guidelines: facts and controversies. Clin Dermatol. 2013;31:382–390. - PubMed
    1. Joly P, Gilbert D, Thomine E, Zitouni M, Ghohestani R, Delpech A, et al. Identification of a new antibody population directed against a desmosomal plaque antigen in Pemphigus and Pemphigus foliaceus. J Invest Dermatol. 1997;108:469–475. - PubMed
    1. Hertl M, Niedermeier A, Borradori L. Autoimmune bullous skin disorders. Ther Umsch. 2010;67:465–482. German. - PubMed
    1. Firooz A, Mazhar A, Ahmed AR. Prevalence of autoimmune diseases in the family members of patients with Pemphigus vulgaris. J Am Acad Dermatol. 1994;31(3 Pt 1):434–437. - PubMed

Publication types

Substances