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Review
. 2016 Jul;253(4):1007-21.
doi: 10.1007/s00709-015-0883-5. Epub 2015 Aug 30.

Centrosome positioning in non-dividing cells

Amy R Barker  1   2 , Kate V McIntosh  1 , Helen R Dawe  3
Affiliations
Review

Centrosome positioning in non-dividing cells

Amy R Barker et al. Protoplasma. 2016 Jul.

Abstract

Centrioles and centrosomes are found in almost all eukaryotic cells, where they are important for organising the microtubule cytoskeleton in both dividing and non-dividing cells. The spatial location of centrioles and centrosomes is tightly controlled and, in non-dividing cells, plays an important part in cell migration, ciliogenesis and immune cell functions. Here, we examine some of the ways that centrosomes are connected to other organelles and how this impacts on cilium formation, cell migration and immune cell function in metazoan cells.

Keywords: Centriole; Centrosome; Cilium; Immunological synapse; Migration.

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