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. 2015 Sep 1;32(3):1004-8.
doi: 10.3305/nh.2015.32.3.9309.

HYPERTRIGLYCERIDEMIC WAIST (EWET), GLYCIDIC AND LIPID PROFILE IN PATIENTS WITH NEWLY DIAGNOSED HEART ATTACK

Veronica Lucas de Olivera Guattini  1 , Carla Haas Piovesan  2 , Estefânia Wittke  3 , Aline Marcadenti  4
Affiliations
Free article

HYPERTRIGLYCERIDEMIC WAIST (EWET), GLYCIDIC AND LIPID PROFILE IN PATIENTS WITH NEWLY DIAGNOSED HEART ATTACK

Veronica Lucas de Olivera Guattini et al. Nutr Hosp. .
Free article

Abstract
in English, Spanish

Introduction: hypertriglyceridemic waist phenotype (EWET) has been poorly tested in patients with established cardiovascular disease.

Objectives: to evaluate a possible association between EWET, glycidic and lipid profile in patients with newly diagnosed heart attack (HA).

Methods: cross-sectional study among 45 inpatients with myocardial infarction. Lipid profile (total cholesterol, HDL-c, LDL-c, serum triglycerides, TC/HDL-c ratio, non-HDL cholesterol) and glycidic profile (fasting glucose, serum insulin, glycated hemoglobin, HOMA-IR, glucose/insulin ratio) were obtained. Weight, height and waist circumferences (WC) were assessed; BMI and EWET were calculated. Analysis of Covariance Models (ANCOVA) was used to assess the objectives.

Results: mean age of participants was 58.75 ± 12.41 years and 55.6% (n = 25) were men. After adjustment for age, gender and BMI, EWET was significantly associated with lower HDL-c (p = 0.02), higher TC/HDL-c ratio (p = 0.003) and a trend toward fasting glucose (p = 0.11).

Conclusion: EWET phenotype seems to be associated with a worse lipidic profile in patients with newly diagnosed HA.

Introducción: el fenotipo de la cintura hipertrigliceridémica (CHT) ha sido poco estudiado en pacientes con enfermedad cardiovascular establecida. Objetivos: evaluar la posible asociación entre el CHT, el perfil glicídico y los lípidos en pacientes con nuevo diagnóstico de infarto. Métodos: estudio transversal en 45 pacientes con infarto de miocardio. Se obtuvieron los lípidos (colesterol total, HDL-c, LDL-c, triglicéridos séricos, relación CT/ HDL-c, colesterol no-HDL) y el perfil glicídico (glucosa, insulina sérica, hemoglobina glucosilada, HOMA-IR, relación glucosa/insulina). Fueron evaluados peso, talla y circunferencia de la cintura (CC); se calcularon el IMC y el CHT. Se utilizó el análisis de los modelos de covarianza (ANCOVA) para evaluar los objetivos. Resultados: la media de edad de los participantes fue de 58,75 ± 12,41 años, y el 55,6% (n = 25) eran hombres. Tras ajustar por edad, sexo y el IMC, el CHT se asoció significativamente con una menor HDL-c (p = 0,02), mayor relación CT/HDL-c (p = 0,003) y una tendencia hacia la glucosa en ayunas (p = 0,11). Conclusión: el fenotipo CHT parece estar asociado con un peor perfil lipídico en pacientes con diagnóstico reciente de infarto.

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