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. 2015 Aug 28:4:27495.
doi: 10.3402/jev.v4.27495. eCollection 2015.

Extracellular RNAs: development as biomarkers of human disease

Joseph F Quinn  1 , Tushar Patel  2 , David Wong  3 , Saumya Das  4 , Jane E Freedman  5 , Louise C Laurent  6 , Bob S Carter  7 , Fred Hochberg  7 , Kendall Van Keuren-Jensen  8 , Matt Huentelman  8 , Robert Spetzler  9 , M Yashar S Kalani  9 , Jorge Arango  10 , P David Adelson  10 , Howard L Weiner  11 , Roopali Gandhi  11 , Beatrice Goilav  12 , Chaim Putterman  13 , Julie A Saugstad  14
Affiliations

Extracellular RNAs: development as biomarkers of human disease

Joseph F Quinn et al. J Extracell Vesicles. .

Abstract

Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as biomarkers in human disease are described. These studies, funded by the NIH Common Fund Extracellular RNA Communication Program, examine diverse extracellular body fluids, including plasma, serum, urine and cerebrospinal fluid. The disorders studied include hepatic and gastric cancer, cardiovascular disease, chronic kidney disease, neurodegenerative disease, brain tumours, intracranial haemorrhage, multiple sclerosis and placental disorders. Progress to date and the plans for future studies are outlined.

Keywords: ERCC; biomarkers; exRNA; extracellular RNA.

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Figures

Fig. 1
Fig. 1
ERCC biomarker groups.
See this image and copyright information in PMC

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