Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Aug;19(8):466-70.
doi: 10.4103/0972-5229.162465.

Correlation of measurement of optic nerve sheath diameter using ultrasound with magnetic resonance imaging

Chetan G Shirodkar  1 , Kartik Munta  1 , S Manimala Rao  1 , M Uma Mahesh  2
Affiliations

Correlation of measurement of optic nerve sheath diameter using ultrasound with magnetic resonance imaging

Chetan G Shirodkar et al. Indian J Crit Care Med. 2015 Aug.

Abstract

Background and aims: Analysis to correlate the measurements of optic nerve sheath diameter (ONSD) obtained by using ultrasound to magnetic resonance imaging (MRI) techniques in order to establish the accuracy of ocular sonography as a noninvasive modality for detecting raised intracranial pressure (ICP).

Materials and methods: A prospective, observational study was performed in 100 cases of adult meningoencephalitis patients admitted to Intensive Care Unit in whom MRI was performed for neurodiagnosis. ONSD was measured in such patients, 3 mm behind the globe in each eye. A mean binocular ONSD >4.6 mm in female and 4.8 mm in male was taken as cut-off values for diagnosing raised ICP. This was compared with ONSD measured on T2-weighted MRI image measured 3 mm behind the globe. The reading obtained from both the methods were compared with Bland-Altman analysis for correlation and the findings were tabulated.

Results: The mean ONSD values measured with ultrasonography (USG) and MRI for female were 5.48 ± 0.43 mm and 5.68 ± 0.44 mm and for male were 5.40 ± 0.37 mm and 5.56 ± 0.38 mm, respectively. The mean age of the female and male was 53.90 ± 17.84 and 56.06 ± 15.67 years, respectively. On comparing ultrasound with MRI-derived ONSD values, we found acceptable agreement between both methods for measurements at a depth of 3 mm (r = 0.02, P < 0.001).

Conclusion: In our study, we have found a good correlation between ocular USG and MRI of ONSD. The study has shown agreement with the fact that ocular sonography can be used as a noninvasive tool for detecting raised ICP with accuracy.

Keywords: Intensive Care Unit; magnetic resonance imaging; ocular sonography; optic nerve sheath diameter; raised intracranial pressure.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: There are no conflicts of interest.

Figures

Figure 1
Figure 1
Measurement of optic nerve sheath diameter by ocular ultrasonography
Figure 2
Figure 2
Measurement of optic nerve sheath diameter on T2-weighted magnetic resonance imaging
Figure 3
Figure 3
Correlation of optic nerve sheath diameter by transorbital sonography and magnetic resonance imaging using Bland– Altman analysis
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Bäuerle J, Nedelmann M. Sonographic assessment of the optic nerve sheath in idiopathic intracranial hypertension. J Neurol. 2011;258:2014–9. - PubMed
    1. Geeraerts T, Merceron S, Benhamou D, Vigué B, Duranteau J. Non-invasive assessment of intracranial pressure using ocular sonography in neurocritical care patients. Intensive Care Med. 2008;34:2062–7. - PubMed
    1. Geeraerts T, Newcombe VF, Coles JP, Abate MG, Perkes IE, Hutchinson PJ, et al. Use of T2-weighted magnetic resonance imaging of the optic nerve sheath to detect raised intracranial pressure. Crit Care. 2008;12:R114. - PMC - PubMed
    1. Killer HE, Jaggi GP, Flammer J, Miller NR, Huber AR, Mironov A. Cerebrospinal fluid dynamics between the intracranial and the subarachnoid space of the optic nerve. Is it always bidirectional? Brain. 2007;130(Pt 2):514–20. - PubMed
    1. Hansen HC, Helmke K. Validation of the optic nerve sheath response to changing cerebrospinal fluid pressure: Ultrasound findings during intrathecal infusion tests. J Neurosurg. 1997;87:34–40. - PubMed

LinkOut - more resources