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. 2013 Dec;39(4):237-43.
doi: 10.5152/tud.2013.060.

The resistance rates of urinary tract infections: Our data from year 2010

Arzu Doğru  1 , Belma Karatoka  2 , Pınar Ergen  1 , Özlem Şen Aydın  1 , Elif Tükenmez Tigen  3
Affiliations

The resistance rates of urinary tract infections: Our data from year 2010

Arzu Doğru et al. Turk J Urol. 2013 Dec.

Abstract

Objective: More than 95% of all urinary tract infections are caused by a single bacterium. Although E. coli is the most common bacterium causing community-acquired infections, Klebsiella spp., enteric gram-negative bacteria and S. saprophyticus have been also identified. This study evaluated the microorganisms isolated from the urine cultures of patients admitted to our outpatient clinics in 2010 and assessed E. coli resistance and the frequency of extended-spectrum beta lactamase (ESBL)-producing bacteria.

Material and methods: In total, 7145 urine cultures were obtained from patients admitted to all clinics between 1 January 2010 and 31 December 2010. The double-disk synergy test was used to identify the presence of ESBL producers.

Results: The most frequently isolated microorganisms were E. coli (60.6%), Enterococcus spp. (10.3%), Klebsiella spp. (7.3%), Pseudomonas spp. (4.8%), and Streptococcus spp. (3.3%). E. coli strains were more resistant to ciprofloxacin (45.12%), trimethoprim-sulfamethoxazole (44.8%) and amoxicillin-clavulanate (31.6%), but they were less likely to be resistant to meropenem (0%), imipenem (0.2%), and amikacin (0.7%). The frequency of ESBL-producing E. coli strains was 14%.

Conclusion: The choice of antibiotic treatment influences the overall success of treatment and the development of resistance, and it is also closely related to the cost of the treatment. As a result, there is a need to review the current treatment protocols. As resistance rates show regional differences, it is necessary to regularly examine regional resistance rates to determine the appropriate empiric antibiotic treatment and reduce costs.

Keywords: E. coli; extended-spectrum beta lactamase; urine culture.

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References

    1. Altoparlak A, Özbek A, Aktaş F. Antibacterial susceptibility rates of bacteria isolated in urinary system infections. Türk Mikrobiyoloji Cemiyeti Dergisi. 2002;32:167–73.
    1. Yılmaz E, Özakın C, Sınırtaş M, Gedikoğlu S. Microorganisms isolated from urine samples in Bacteriology Laboratories of Uludağ University Faculty of Medicine between the years 1999, and 2002, and their antibacterial susceptibity rates. İnfeksiyon Dergisi. 2005;19:91–6.
    1. Ateş F. Analysis of our urine culture results in patients with lower urinary system infections. Turkish Journal of Urology. 2007;33:223–7.
    1. Temiz H, Akkoç H, Gül K. Antibacterial resistance of gram-negative bacteria isolated from urine cultures performed in our laboratory. Dicle Tıp Dergisi. 2008;35:234–9.
    1. Gündüz T, Mumcuoğlu İ. Antibacterial susceptibilities of Escherichia coli isolated from urine samples. Türk Mikrobiyoloji Cemiyeti Dergisi. 2004;34:157–61.

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