Radiotherapy dosimetry audit: three decades of improving standards and accuracy in UK clinical practice and trials
- PMID: 26329469
- PMCID: PMC4743452
- DOI: 10.1259/bjr.20150251
Radiotherapy dosimetry audit: three decades of improving standards and accuracy in UK clinical practice and trials
Abstract
Dosimetry audit plays an important role in the development and safety of radiotherapy. National and large scale audits are able to set, maintain and improve standards, as well as having the potential to identify issues which may cause harm to patients. They can support implementation of complex techniques and can facilitate awareness and understanding of any issues which may exist by benchmarking centres with similar equipment. This review examines the development of dosimetry audit in the UK over the past 30 years, including the involvement of the UK in international audits. A summary of audit results is given, with an overview of methodologies employed and lessons learnt. Recent and forthcoming more complex audits are considered, with a focus on future needs including the arrival of proton therapy in the UK and other advanced techniques such as four-dimensional radiotherapy delivery and verification, stereotactic radiotherapy and MR linear accelerators. The work of the main quality assurance and auditing bodies is discussed, including how they are working together to streamline audit and to ensure that all radiotherapy centres are involved. Undertaking regular external audit motivates centres to modernize and develop techniques and provides assurance, not only that radiotherapy is planned and delivered accurately but also that the patient dose delivered is as prescribed.
Figures
Similar articles
-
An external dosimetry audit programme to credential static and rotational IMRT delivery for clinical trials quality assurance.Phys Med. 2017 Mar;35:25-30. doi: 10.1016/j.ejmp.2017.02.012. Epub 2017 Feb 22. Phys Med. 2017. PMID: 28236559
-
Analysis of regional radiotherapy dosimetry audit data and recommendations for future audits.Br J Radiol. 2011 Aug;84(1004):733-42. doi: 10.1259/bjr/18691638. Epub 2010 Dec 15. Br J Radiol. 2011. PMID: 21159805 Free PMC article.
-
50 Years of the IAEA/WHO postal dose audit programme for radiotherapy: what can we learn from 13756 results?Acta Oncol. 2020 May;59(5):495-502. doi: 10.1080/0284186X.2020.1723162. Epub 2020 Feb 8. Acta Oncol. 2020. PMID: 32036736
-
The role of dosimetry audit in lung SBRT multi-centre clinical trials.Phys Med. 2017 Dec;44:171-176. doi: 10.1016/j.ejmp.2017.04.003. Epub 2017 Apr 5. Phys Med. 2017. PMID: 28391958 Review.
-
Novel methodologies for dosimetry audits: Adapting to advanced radiotherapy techniques.Phys Imaging Radiat Oncol. 2018 Mar 19;5:76-84. doi: 10.1016/j.phro.2018.03.002. eCollection 2018 Jan. Phys Imaging Radiat Oncol. 2018. PMID: 33458373 Free PMC article. Review.
Cited by
-
Dosimetric end-to-end tests in a national audit of 3D conformal radiotherapy.Phys Imaging Radiat Oncol. 2018 Apr 24;6:5-11. doi: 10.1016/j.phro.2018.03.006. eCollection 2018 Apr. Phys Imaging Radiat Oncol. 2018. PMID: 33458381 Free PMC article.
-
Evaluation of a generalized knowledge-based planning performance for VMAT irradiation of breast and locoregional lymph nodes-Internal mammary and/or supraclavicular regions.PLoS One. 2021 Jan 15;16(1):e0245305. doi: 10.1371/journal.pone.0245305. eCollection 2021. PLoS One. 2021. PMID: 33449952 Free PMC article.
-
A remote EPID-based dosimetric TPS-planned audit of centers for clinical trials: outcomes and analysis of contributing factors.Radiat Oncol. 2018 Sep 17;13(1):178. doi: 10.1186/s13014-018-1125-8. Radiat Oncol. 2018. PMID: 30223857 Free PMC article.
-
Optimised conformal total body irradiation: a heterogeneous practice, so where next?Br J Radiol. 2023 Mar 1;96(1144):20220650. doi: 10.1259/bjr.20220650. Epub 2023 Jan 14. Br J Radiol. 2023. PMID: 36475820 Free PMC article. Review.
-
The impact of Clinical Trials Radiographers on set-up and recruitment to radiotherapy trials.Tech Innov Patient Support Radiat Oncol. 2025 Apr 4;34:100309. doi: 10.1016/j.tipsro.2025.100309. eCollection 2025 Jun. Tech Innov Patient Support Radiat Oncol. 2025. PMID: 40290343 Free PMC article.
References
-
- International Commission on Radiation Units and Measurements. Determination of absorbed dose in a patient irradiated by beams of X or gamma rays in radiotherapy procedures. ICRU report 24. Bethesda, MD: IRCU; 1976.
-
- Dobbs J, Thwaites D. Quality assurance and its conceptual framework. In: Mayles WPM, Lake R, Mckenzie A, Macaulay EM, Morgan HM, Jordan TJ, Powley SK, eds. Physics aspects of quality control in radiotherapy in IPEM report 81. York, UK: IPEM; 1999.
-
- Thwaites D. Accuracy required and achievable in radiotherapy dosimetry: have modern technology and techniques changed our views? J Phys Conf Ser 2013; 444: 2006.
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous