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Case Reports
. 2015 Dec;26(4):324-7.
doi: 10.1007/s12022-015-9392-5.

Synchronous Thyroid Involvement in Plasma Cell Leukemia Masquerading as Hashimoto's Thyroiditis: Role of Ancillary Cytology Techniques in Diagnostic Workup

Ashwani Tandon  1 , T Roshni Paul  2 , Rekha Singh  3 , A M V R Narendra  4
Affiliations
Case Reports

Synchronous Thyroid Involvement in Plasma Cell Leukemia Masquerading as Hashimoto's Thyroiditis: Role of Ancillary Cytology Techniques in Diagnostic Workup

Ashwani Tandon et al. Endocr Pathol. 2015 Dec.

Abstract

Neoplastic plasma cell involvement of thyroid is an uncommon condition, and it may involve thyroid in multiple myeloma or solitary plasmacytoma. Its clinical and pathological features are not well understood. We present a rare case of synchronous thyroid involvement in plasma cell leukemia presenting as thyroid nodule with primary hypothyroidism. Simultaneous cytology, immunocytochemistry, FISH analysis with 13q14.3 and TP53 on cytology smears and haematology workup were performed to diagnose and to understand disease pathobiology with poor outcome.

Keywords: FISH; Hashimoto’s thyroiditis; Plasma cell leukemia; Thyroid.

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References

    1. J Cytol. 2014 Jan;31(1):53-6 - PubMed
    1. Blood. 2012 Aug 2;120(5):1060-6 - PubMed
    1. Indian J Hematol Blood Transfus. 2014 Sep;30(Suppl 1):390-3 - PubMed
    1. Ann Otolaryngol. 1950 Nov-Dec;67(11-12):826-8 - PubMed
    1. Int J Hematol. 2011 Jun;93(6):825-6 - PubMed

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