Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Jul 1;7(3):e419-27.
doi: 10.4317/jced.52127. eCollection 2015 Jul.

Oral manifestations of HIV/AIDS in Asia: Systematic review and future research guidelines

Gaurav Sharma  1 , Sukhvinder-Singh Oberoi  2 , Puneeta Vohra  3 , Archna Nagpal  4
Affiliations
Review

Oral manifestations of HIV/AIDS in Asia: Systematic review and future research guidelines

Gaurav Sharma et al. J Clin Exp Dent. .

Abstract

Objectives: The authors have conducted a systematic review of oral manifestations of HIV from studies conducted in Asia to establish the characteristics and prevalence of individual oral manifestations in Asia, and to assess the direction of future research studies on oral manifestations of HIV in Asia.

Material and methods: The electronic retrieval systems and databases searched for relevant articles were PubMed [MEDLINE], EBSCO, and EMBASE. The search was for limited articles published in English or with an English abstract and articles published during the period January 1995 to August 2014. The authors reached a final overall sample of 39 studies that were conducted in Asia.

Results: The median population size among all studies was 312.7 patients. Oral candidiasis [OC] was the most common oral manifestation [37.7%] in studies conducted in Asia. The overall prevalence of oral hairy leukoplakia and melanotic hyperpigmentation was computed to be 10.1% and 22.8% respectively. Thailand and India are primarily countries with maximum research on oral manifestations.

Conclusions: The research on oral manifestations of HIV in Asia has to upgrade to more interventional and therapeutic studies rather than the contemporary cross- sectional epidemiological descriptive studies. The authors have given suggestions and future directions for the implementation of clinical research of oral manifestations in HIV patients. Key words:Oral manifestations, HIV/AIDS, Asia, Systematic review.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Scatter diagram showing oral candidiasis prevalence in the conducted studies on oral manifestations in HIV.
Figure 2
Figure 2
Scatter diagram showing oral hairy leukoplakia prevalence in conducted studies on oral manifestations in HIV.
See this image and copyright information in PMC

References

    1. Arendorf T, Holmes H. Oral manifestations associated with human immunodeficiency virus (HIV) infection in developing countries – are there differences from developed countries? Oral Dis. 2000;6:133–5. - PubMed
    1. Sroussi HY, Villines D, Epstein J, Alves MC, Alves ME. Oral lesions in HIV positive dental patient - one more argument for tobacco cessation. Oral Dis. 2007;13:324–8. - PubMed
    1. Ranganathan K, Hemalatha R. Oral lesions in HIV in developing countries: An overview. Adv Dent Res. 2006;19:63–8. - PubMed
    1. Anil S, Challacombe SJ. Oral Lesions of HIV and AIDS in Asia: an overview. Oral Dis. 1997;3:S36–40. - PubMed
    1. Nittayananta W, Jealae S, Chungpanich S. Oral lesions in Thai heterosexual AIDS patient. Br Dent J. 1997;182:219–21. - PubMed

LinkOut - more resources