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Review
. 2015 Jul-Sep;27(3):266-73.
doi: 10.5935/0103-507X.20150035. Epub 2015 Aug 28.

Progress and perspectives in pediatric acute respiratory distress syndrome

[Article in English, Portuguese]
Alexandre Tellechea Rotta  1 , Jefferson Pedro Piva  2 , Cinara Andreolio  3 , Werther Brunow de Carvalho  4 , Pedro Celiny Ramos Garcia  5
Affiliations
Review

Progress and perspectives in pediatric acute respiratory distress syndrome

[Article in English, Portuguese]
Alexandre Tellechea Rotta et al. Rev Bras Ter Intensiva. 2015 Jul-Sep.

Abstract
in English, Portuguese

Acute respiratory distress syndrome is a disease of acute onset characterized by hypoxemia and infiltrates on chest radiographs that affects both adults and children of all ages. It is an important cause of respiratory failure in pediatric intensive care units and is associated with significant morbidity and mortality. Nevertheless, until recently, the definitions and diagnostic criteria for acute respiratory distress syndrome have focused on the adult population. In this article, we review the evolution of the definition of acute respiratory distress syndrome over nearly five decades, with a special focus on the new pediatric definition. We also discuss recommendations for the implementation of mechanical ventilation strategies in the treatment of acute respiratory distress syndrome in children and the use of adjuvant therapies.

A síndrome do desconforto respiratório agudo é uma patologia de início agudo, marcada por hipoxemia e infiltrados na radiografia de tórax, acometendo tanto adultos quanto crianças de todas as faixas etárias. Ela é causa importante de insuficiência respiratória em unidades de terapia intensiva pediátrica associada a significativa morbidade e mortalidade. Apesar disso, até recentemente, as definições e os critérios diagnósticos para síndrome do desconforto respiratório agudo centravam-se na população adulta. No presente artigo, revisamos a evolução da definição da síndrome do desconforto respiratório agudo ao longo de quase cinco décadas, com foco especial na nova definição pediátrica. Discutimos ainda recomendações relativas à aplicação de estratégias de ventilação mecânica no tratamento da síndrome do desconforto respiratório agudo em crianças, assim como o uso de terapias adjuvantes.

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Conflict of interest statement

Conflicts of interest: None.

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