Paradoxical Role of IL-17 in Progression of Diabetic Nephropathy
- PMID: 26334029
- PMCID: PMC4769213
- DOI: 10.1681/ASN.2015070813
Paradoxical Role of IL-17 in Progression of Diabetic Nephropathy
Keywords: cytokines; diabetic nephropathy; glomerular epithelial cells; kidney.
Comment on
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Low-Dose IL-17 Therapy Prevents and Reverses Diabetic Nephropathy, Metabolic Syndrome, and Associated Organ Fibrosis.J Am Soc Nephrol. 2016 Mar;27(3):745-65. doi: 10.1681/ASN.2014111136. Epub 2015 Sep 2. J Am Soc Nephrol. 2016. PMID: 26334030 Free PMC article.
References
-
- Nakajima K, Kanda T, Takaishi M, Shiga T, Miyoshi K, Nakajima H, Kamijima R, Tarutani M, Benson JM, Elloso MM, Gutshall LL, Naso MF, Iwakura Y, DiGiovanni J, Sano S: Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesions in a mouse model. J Immunol 186: 4481–4489, 2011 - PubMed
-
- Kuriya G, Uchida T, Akazawa S, Kobayashi M, Nakamura K, Satoh T, Horie I, Kawasaki E, Yamasaki H, Yu L, Iwakura Y, Sasaki H, Nagayama Y, Kawakami A, Abiru N: Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse. Diabetologia 56: 1773–1780, 2013 - PubMed
-
- Krebs CF, Lange S, Niemann G, Rosendahl A, Lehners A, Meyer-Schwesinger C, Stahl RA, Benndorf RA, Velden J, Paust HJ, Panzer U, Ehmke H, Wenzel UO: Deficiency of the interleukin 17/23 axis accelerates renal injury in mice with deoxycorticosterone acetate+angiotensin ii-induced hypertension. Hypertension 63: 565–571, 2014 - PubMed
-
- Kim SM, Lee SH, Lee A, Kim DJ, Kim YG, Kim SY, Jeong KH, Lee TW, Ihm CG, Lim SJ, Moon JY: Targeting T helper 17 by mycophenolate mofetil attenuates diabetic nephropathy progression [published online ahead of print May 5, 2015]. Transl Res 10.1016/j.trsl.2015.04.013 - PubMed
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