Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2016 Mar;27(3):657-8.
doi: 10.1681/ASN.2015070813. Epub 2015 Sep 2.

Paradoxical Role of IL-17 in Progression of Diabetic Nephropathy

Affiliations
Editorial

Paradoxical Role of IL-17 in Progression of Diabetic Nephropathy

Daniel L Galvan et al. J Am Soc Nephrol. 2016 Mar.
No abstract available

Keywords: cytokines; diabetic nephropathy; glomerular epithelial cells; kidney.

PubMed Disclaimer

Comment on

References

    1. Nakajima K, Kanda T, Takaishi M, Shiga T, Miyoshi K, Nakajima H, Kamijima R, Tarutani M, Benson JM, Elloso MM, Gutshall LL, Naso MF, Iwakura Y, DiGiovanni J, Sano S: Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesions in a mouse model. J Immunol 186: 4481–4489, 2011 - PubMed
    1. Kuriya G, Uchida T, Akazawa S, Kobayashi M, Nakamura K, Satoh T, Horie I, Kawasaki E, Yamasaki H, Yu L, Iwakura Y, Sasaki H, Nagayama Y, Kawakami A, Abiru N: Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse. Diabetologia 56: 1773–1780, 2013 - PubMed
    1. Krebs CF, Lange S, Niemann G, Rosendahl A, Lehners A, Meyer-Schwesinger C, Stahl RA, Benndorf RA, Velden J, Paust HJ, Panzer U, Ehmke H, Wenzel UO: Deficiency of the interleukin 17/23 axis accelerates renal injury in mice with deoxycorticosterone acetate+angiotensin ii-induced hypertension. Hypertension 63: 565–571, 2014 - PubMed
    1. Walker LS, von Herrath M: CD4 T cell differentiation in type 1 diabetes [published online ahead of print June 23, 2015]. Clin Exp Immunol 10.1111/cei.12672 - PMC - PubMed
    1. Kim SM, Lee SH, Lee A, Kim DJ, Kim YG, Kim SY, Jeong KH, Lee TW, Ihm CG, Lim SJ, Moon JY: Targeting T helper 17 by mycophenolate mofetil attenuates diabetic nephropathy progression [published online ahead of print May 5, 2015]. Transl Res 10.1016/j.trsl.2015.04.013 - PubMed

MeSH terms