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Review
. 2015 Sep 3:51:2.15.1-2.15.6.
doi: 10.1002/0471250953.bi0215s51.

DNA Motif Databases and Their Uses

Gary D Stormo  1
Affiliations
Review

DNA Motif Databases and Their Uses

Gary D Stormo. Curr Protoc Bioinformatics. .

Abstract

Transcription factors (TFs) recognize and bind to specific DNA sequences. The specificity of a TF is usually represented as a position weight matrix (PWM). Several databases of DNA motifs exist and are used in biological research to address important biological questions. This overview describes PWMs and some of the most commonly used motif databases, as well as a few of their common applications.

Keywords: DNA motifs; binding site predictions; position weight matrices; transcription factors.

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References

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