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Review
. 2016 Mar 3;12(3):773-8.
doi: 10.1080/21645515.2015.1086519.

Healthy adult vaccination: An urgent need to prevent hepatitis B in China

Yan Qiu  1 , Jingjing Ren  1 , Jun Yao  2
Affiliations
Review

Healthy adult vaccination: An urgent need to prevent hepatitis B in China

Yan Qiu et al. Hum Vaccin Immunother. .

Abstract

Prevalence of hepatitis B is still high among adults in China, athough the prevalence in children has decreased dramatically. Immunization against hepatitis B among adults is urgently required. Through analyzing the immunogenicity of different doses, schedules and booster immunization among adults, we recommend 10 or 20 μg with a 0-1-6-month schedule or a 0-1-12-month schedule for migrant adults. For immunity failure, increasing the dose or covalent vaccine is suggested to provide protective antibodies. To enhance immunity among adults, hepatitis B vaccine should be included in health insurance.

Keywords: China; healthy adults; hepatitis B; immunization; prevalence.

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Figures

Figure 1.
Figure 1.
The comparison of HBsAg positive rate of population aged 1–59 years in 1979, 1992 and 2006.
See this image and copyright information in PMC

References

    1. Bureau of disease prevention and control of Ministry of health, Chinese Center for disease control and prevention Sero-epidemiological survey of hepatitis B among national population. Beijing: People's Medical Press; 2011
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    1. Zhou B, Cao DQ, Zhang YH, et al.. Epide-miological characteristics of viral hepatitis in Mentou district of Beijing. Capital J Public Health 2011; 5:14-7.

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