[Acute idiopathic thrombocytopenic purpura after anti-influenza vaccination]

Abstract

A case of acute thrombocytopenic purpura, presented with sudden onset of petechiae and ecchymoses, as a possible complication of antinfluenza vaccination with inactivated viruses is reported. Within 15 days of vaccination the platelet count fell down, serum antiplatelet antibodies were detected in high titre and bone marrow aspiration revealed an increased number of megakaryocytes. Corticosteroid therapy was followed by a complete recovery within ten days; three months later, platelets number remained in the normal range.