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. 2016 Jan;33(1):84-93.
doi: 10.1002/da.22404. Epub 2015 Sep 7.

PATHOLOGICAL PERSONALITY TRAITS AND THE NATURALISTIC COURSE OF INTERNALIZING DISORDERS AMONG HIGH-RISK YOUNG ADULTS

Christopher C Conway  1 , Michelle G Craske  2 , Richard E Zinbarg  3   4 , Susan Mineka  3
Affiliations

PATHOLOGICAL PERSONALITY TRAITS AND THE NATURALISTIC COURSE OF INTERNALIZING DISORDERS AMONG HIGH-RISK YOUNG ADULTS

Christopher C Conway et al. Depress Anxiety. 2016 Jan.

Abstract

Background: A personality disorder diagnosis signals a negative prognosis for depressive and anxiety disorders, but the precise abnormal personality traits that determine the temporal course of internalizing psychopathology are unknown. In the present study, we examined prospective associations between abnormal personality traits and the onset and recurrence of internalizing disorders.

Methods: A sample of 371 young adults at high risk for internalizing problems completed the Schedule for Nonadaptive and Adaptive Personality-Second Edition--a measure of 12 abnormal personality traits and three temperament dimensions (i.e., Negative Temperament, Positive Temperament, Disinhibition vs. Control)--and underwent annual diagnostic interviews over 4 years of follow-up.

Results: In multivariate survival analyses, Negative Temperament was a robust predictor of both new onsets and recurrences of internalizing disorder. Further, the Dependency and Self-Harm abnormal personality dimensions emerged as independent predictors of new onsets and recurrences, respectively, of internalizing disorders after statistically adjusting for variation in temperament.

Conclusions: Our findings suggest that abnormal personality traits and temperament dimensions have complementary effects on the trajectory of internalizing pathology during young adulthood. In assessment and treatment settings, targeting the abnormal personality and temperament dimensions with the greatest prognostic value stands to improve the early detection of enduring internalizing psychopathology.

Keywords: anxiety; depression; internalizing disorders; naturalistic course; personality pathology; prognosis; temperament.

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Conflict of interest statement

Conflict of Interest Disclosure: Drs. Craske, Mineka, and Zinbarg report grant funding from the National Institute of Mental Health during the conduct of the study.

Figures

Figure 1
Figure 1
Cumulative incidence function for the new onset of any internalizing disorder as a function of Dependency. “Very low” and “very high” refer to two standard deviations from the mean of Dependency, and “low” and “high” refer to one standard deviation from the mean.
Figure 2
Figure 2
Cumulative incidence function for the recurrence of any internalizing disorder as a function of Self-Harm. “Very low” and “very high” refer to two standard deviations from the mean of Self-Harm, and “low” and “high” refer to one standard deviation from the mean.
See this image and copyright information in PMC

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