THE metabolic syndrome and accurate cardiovascular risk prediction in persons with type 2 diabetes mellitus

Abstract

Background: Persons with type 2 DM have a cardiovascular risk 2-4 times that of the normal population. Co-occurrence of metabolic syndrome (MS) with type 2 DM is associated with an increased risk of development of cardiovascular disease. The aim of this study was to determine the prevalence of the MS in patients with type 2 diabetes mellitus and to compare absolute cardiovascular risk in type 2 DM Patients with MS with those without MS.

Methods: Anthropometric measurements and Blood Pressure of 340 eligible patients with type 2 DM recruited into the study were taken. Participants' FPG, FLP and glycated haemoglobin were also estimated. Cardiovascular risk score was calculated using the United Kingdom Prospective Diabetes Study (UKPDS) risk engine. Diagnosis of the MS was the International Diabetes Federation Criteria (IDF).

Results: Over 66% participants had MS. The absolute cardiovascular risk score was found to be similar in persons with type 2 DM whether they fulfilled the criteria for diagnosis metabolic syndrome or not.

Conclusion: The absolute cardiovascular risk score was similar in type 2 DM patients with or without the metabolic syndrome.

Keywords: Calculated absolute cardiovascular risk; Metabolic syndrome; Type 2 diabetes mellitus; UKPDS risk engine.