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. 2015:2015:208519.
doi: 10.1155/2015/208519. Epub 2015 Aug 11.

Prevalence and Risk Factors for Oral Potentially Malignant Disorders in Indian Population

Sandeep Kumar  1 , Nitai Debnath  2 , Mohammed B Ismail  3 , Arunoday Kumar  4 , Amit Kumar  5 , Bhumika K Badiyani  5 , Pavan K Dubey  6 , Laxmi V Sukhtankar  7
Affiliations

Prevalence and Risk Factors for Oral Potentially Malignant Disorders in Indian Population

Sandeep Kumar et al. Adv Prev Med. 2015.

Abstract

Objective. To assess the prevalence of oral potentially malignant disorders and to determine the potential risk factors for its development in Indian population. Materials and Methods. This cross-sectional study was carried out on 1241 individuals in Indore, Madhya Pradesh. A questionnaire was designed to record information about sociodemographic characteristics, oral hygiene practices, dietary habits, and risk factors for oral potentially malignant disorders. Oral mucosal lesions were examined by a skilled person. Results. The overall prevalence of oral potentially malignant disorders was found to be 13.7% with oral submucous fibrosis (8.06%) found to be more common and erythroplakia (0.24%) found to be least prevalent. Results of Logistic Regression analysis showed that males (OR = 2.09, P value < 0.0001) who were ever consumers of tobacco (OR = 2.06, P value = 0.030) and areca nut chewing (OR = 2.64, P value = 0.004) were more likely to develop oral potentially malignant disorders compared to never consumers. Diabetic (OR = 2.21, P value = 0.014) and underweight individuals (OR = 2.23, P value = 0.007) were more likely to suffer from oral potentially malignant disorders. Conclusion. The study reinforces the association of tobacco and areca nut consumption with oral potentially malignant disorders. An association of oral potentially malignant disorders with diabetes and BMI was confirmed by this study.

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References

    1. Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncology. 2009;45(4-5):309–316. doi: 10.1016/j.oraloncology.2008.06.002. - DOI - PubMed
    1. Gupta P. C., Mehta F. S., Daftary D. K., et al. Incidence rates of oral cancer and natural history of oral precancerous lesions in a 10-year follow-up study of Indian villagers. Community Dentistry and Oral Epidemiology. 1980;8(6):287–333. doi: 10.1111/j.1600-0528.1980.tb01302.x. - DOI - PubMed
    1. Bouquot J. E., Whitaker S. B. Oral leukoplakia—rationale for diagnosis and prognosis of its clinical subtypes or ‘phases’. Quintessence International. 1994;25(2):133–140. - PubMed
    1. Murti P. R., Bhonsle R. B., Pindborg J. J., Daftary D. K., Gupta P. C., Mehta F. S. Malignant transformation rate in oral submucous fibrosis over a 17-year period. Community Dentistry and Oral Epidemiology. 1985;13(6):340–341. doi: 10.1111/j.1600-0528.1985.tb00468.x. - DOI - PubMed
    1. Thomas G., Hashibe M., Jacob B. J., et al. Risk factors for multiple oral premalignant lesions. International Journal of Cancer. 2003;107(2):285–291. doi: 10.1002/ijc.11383. - DOI - PubMed

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