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. 2015:2015:465450.
doi: 10.1155/2015/465450. Epub 2015 Aug 12.

Osseous Metaplasia in Mucinous Tubular and Spindle Cell Carcinoma of the Kidney: A Case of Massive, Bilateral Tumors

Aeen M Asghar  1 , Matthew A Uhlman  2 , Laila Dahmoush  3 , Sundeep Deorah  2
Affiliations

Osseous Metaplasia in Mucinous Tubular and Spindle Cell Carcinoma of the Kidney: A Case of Massive, Bilateral Tumors

Aeen M Asghar et al. Case Rep Urol. 2015.

Abstract

Renal cell carcinoma (RCC) is the most common kidney malignancy, with many histologic subtypes. One of the rare forms of RCC is mucinous tubular and spindle cell carcinoma (MTSCC), which is newly described with limited information on clinical picture and outcome. Heterotopic bone formation (osseous metaplasia) is a rare finding within any renal mass. Here we report a case of a massive, bilateral MTSCC with histologic findings of heterotopic bone formation, which has not been described before.

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Figures

Figure 1
Figure 1
Preoperative abdominal MRI.
Figure 2
Figure 2
Gross left kidney with mucinous tubular and spindle cell carcinoma.
Figure 3
Figure 3
Tumor cells forming merging tubules containing mucin.
Figure 4
Figure 4
Tumor cells showing spindle cell morphology at the center.
Figure 5
Figure 5
Bone trabeculae are seen adjacent to tumor cells.
See this image and copyright information in PMC

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