Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Nov;23(11):548-54.
doi: 10.1007/s12471-015-0743-0.

Trends in incidence of infective endocarditis at the Medical Center of Alkmaar

Affiliations

Trends in incidence of infective endocarditis at the Medical Center of Alkmaar

M M G Krul et al. Neth Heart J. 2015 Nov.

Abstract

Introduction: Infective endocarditis (IE) is a life-threatening illness with a high morbidity and mortality, and with a rise in incidence in patients with prosthetic valves and cardiac devices. Recently the Dutch guidelines of IE prophylaxis have been revised, limiting IE prophylaxis to the highest-risk population. The aim of the present study was to investigate the incidence of IE and its trend between 2008-2013 in a regional hospital in the Netherlands.

Methods: This is an observational descriptive study of all patients who were admitted with IE to the Medical Center of Alkmaar (MCA) from 1 January 2008 to 31 December 2013.

Results: A total of 89 patients with IE, including 7 patients (7.9 %) with a cardiac device IE (CDIE), were identified. In 2008 there were 8 patients with IE, this increased to 26 patients in 2013. Patients with a prosthetic valve IE increased from 25 % in 2008 to 34.6 % in 2013. This increase was not seen in patients with CDIE.

Conclusion: In the MCA we have observed an increase in patients with IE since 2010. This increase was in part attributable to prosthetic valve IE. A larger observational study is needed to investigate the increase of IE in the Netherlands.

Keywords: Cardiac device; Endocarditis prophylaxis; Infective endocarditis; Prosthetic valve.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Number of patients with infective endocarditis, prosthetic valve endocarditis and CDIE between 2008–2013

References

    1. Baddour LM, Wilson WR, Bayer AS. Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, and the Councils on Clinical Cardiology, Stroke, and Cardiovascular Surgery and Anesthesia, American Heart Association: endorsed by the Infectious Diseases Society of America. Circulation. 2005;111:e394–434. doi: 10.1161/CIRCULATIONAHA.105.165564. - DOI - PubMed
    1. Griffin MR, Wilson WR, Edwards WD. Infective endocarditis. Olmsted County, Minnesota, 1950 through 1981. JAMA. 1985;254:1199–202. doi: 10.1001/jama.1985.03360090089026. - DOI - PubMed
    1. Mylonakis E, Calderwood SB. Infective endocarditis in adults. N Engl J Med. 2001;345:1318–30. doi: 10.1056/NEJMra010082. - DOI - PubMed
    1. Bor DH, Woolhandler S, Nardin R. Infective endocarditis in the U.S., 1998-2009: a nationwide study. PLoS One. 2013;8:e60033. doi: 10.1371/journal.pone.0060033. - DOI - PMC - PubMed
    1. Murdoch DR, Corey GR, Hoen B. Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study. Arch Intern Med. 2009;169:463–73. doi: 10.1001/archinternmed.2008.603. - DOI - PMC - PubMed

LinkOut - more resources