Comment
doi: 10.1126/scitranslmed.aad1255.
NS1: A corner piece in the dengue pathogenesis puzzle?
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- PMID: 26355028
- DOI: 10.1126/scitranslmed.aad1255
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Comment
NS1: A corner piece in the dengue pathogenesis puzzle?
Sci Transl Med.
.
Abstract
Soluble dengue virus NS1 protein induces proinflammatory immune responses via Toll-like receptor 4 and disrupts endothelial cell integrity, resulting in vascular leakage (Beatty et al. and Modhiran et al., this issue).
Copyright © 2015, American Association for the Advancement of Science.
Comment on
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Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination.Sci Transl Med. 2015 Sep 9;7(304):304ra141. doi: 10.1126/scitranslmed.aaa3787. Sci Transl Med. 2015. PMID: 26355030
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Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity.Sci Transl Med. 2015 Sep 9;7(304):304ra142. doi: 10.1126/scitranslmed.aaa3863. Sci Transl Med. 2015. PMID: 26355031
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