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Comparative Study
. 2016 Jan;22(1):141-5.
doi: 10.1097/MIB.0000000000000582.

Mortality and Causes of Death in Ulcerative Colitis: Results from 20 Years of Follow-up in the IBSEN Study

Øistein Hovde  1 , Milada C Småstuen, Marte L Høivik, Tomm Bernklev, Gert Huppertz-Hauss, Ole Høie, Jørgen Jahnsen, Njaal Stray, Magne Henriksen, Inger C Solberg, Bjørn A Moum
Affiliations
Comparative Study

Mortality and Causes of Death in Ulcerative Colitis: Results from 20 Years of Follow-up in the IBSEN Study

Øistein Hovde et al. Inflamm Bowel Dis. 2016 Jan.

Abstract

Background: The best way to obtain knowledge about the natural history, including mortality, of ulcerative colitis (UC) is to conduct a longitudinal, population-based, prospective study. The aims of this study were to calculate the mortality rates and causes of death in patients with UC.

Methods: A prospective, population-based, longitudinal cohort study was conducted in South-Eastern Norway. A total of 519 patients (51.4% men) with UC were included over a 4-year period. A gastroenterologist from a university hospital reviewed the clinical information of all of the patients. Mortality data were retrieved from the Cause of Death Registry and from Statistics Norway.

Results: No statistically significant increases in total mortality or cause-specific mortality between the patients with UC and the controls were found.

Conclusions: The present 20-year population-based cohort study revealed a good prognosis regarding the mortality, which partially might be explained by the patients' coverage by a generally well-functioning health care system.

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