Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2015 Oct 13;6(31):30427-8.
doi: 10.18632/oncotarget.5445.

Priming persistence of HCV

Anita Schuch  1   2 , Robert Thimme  1 , Maike Hofmann  1
Affiliations
Editorial

Priming persistence of HCV

Anita Schuch et al. Oncotarget. .
No abstract available

Keywords: CD8+ T-cells; HCV; priming.

PubMed Disclaimer

Figures

Figure 1
Figure 1. Mechanisms underlying HCV persistence reflected by CD8+ T-cell differentiation
Beside viral escape and prolonged antigen exposure, lack of priming can cause impaired CD8+ T-cell responses and viral persistence in chronic HCV infection. These different mechanisms are reflected by diverse differentiation states of HCV-specific CD8+ T-cells.
See this image and copyright information in PMC

Comment on

References

    1. Bengsch B, et al. PLoS Pathog. 2010;6:e1000947. - PMC - PubMed
    1. Obar JJ, et al. Immunity. 2008;28:859–869. - PMC - PubMed
    1. Alanio C, et al. Blood. 2010;115:3718–3725. - PubMed
    1. Schmidt J, et al. J Virol. 2011;85:5232–5236. - PMC - PubMed
    1. Nitschke K, et al. J Virol. 2015;89:25–34. - PMC - PubMed