Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2015 Sep 10;162(6):1208-10.
doi: 10.1016/j.cell.2015.08.053.

Single-Cell Analysis: The Differences That Kill

Savaş Tay  1
Affiliations
Free article
Comment

Single-Cell Analysis: The Differences That Kill

Savaş Tay. Cell. .
Free article

Abstract

Using single-cell RNA sequencing, Avraham et al. investigate how variability in macrophage response to infection is controlled by variability within the pathogen population. They find that heterogeneous expression of the Salmonella virulence factor PhoP and subsequent cell-wall modifications lead to the bimodal induction of the interferon-response in infected macrophages.

PubMed Disclaimer

Comment on

MeSH terms

LinkOut - more resources