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Case Reports
. 2015 Sep;47(7):2301-3.
doi: 10.1016/j.transproceed.2015.07.005.

Early Post-transplant Lymphoproliferative Disease in the Donor Ureter Without Systemic Involvement: A Case Report

W M Bennett  1 , T D Batiuk  2 , K M McEvoy  2 , V Douzdjian  2 , J Hyde  3 , C Shaut  4 , G M Segal  5
Affiliations
Case Reports

Early Post-transplant Lymphoproliferative Disease in the Donor Ureter Without Systemic Involvement: A Case Report

W M Bennett et al. Transplant Proc. 2015 Sep.

Abstract

Background: Post-transplant lymphoproliferative disease is a serious complication of renal transplantation. Major risk factors include Epstein-Barr virus (EBV) seronegativity and induction immunosuppression with lymphocyte-depleting agents.

Results: We present a case of a 50-year year-old woman with very early onset PTLD confined to the donor ureter. Phenotypic studies on the tumor material reveal that the lymphoma was most likely of donor origin. A complete staging workup including the kidney allograft was negative for any other sites of involvement.

Conclusions: This case, which had a fatal outcome, emphasizes the risk of renal transplantation in BV-negative individuals when given induction with lymphocyte-depleting drugs.

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