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. 2015 Aug;32(4):312-6.
doi: 10.5114/pdia.2015.48043. Epub 2015 Aug 12.

Dermoscopy of nodular skin metastases from the gastrointestinal primary cancer

Grażyna Kamińska-Winciorek  1 , Jerzy Wydmański  2 , Krzysztof Januszewski  3 , Wojciech Silny  4
Affiliations

Dermoscopy of nodular skin metastases from the gastrointestinal primary cancer

Grażyna Kamińska-Winciorek et al. Postepy Dermatol Alergol. 2015 Aug.
No abstract available

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Figures

Figure 1
Figure 1
A case of a macroscopic skin metastatic nodule from sigmoid colon cancer. This case shows a solitary, small, palpable, firm, slightly painful nodule of 1.5 cm in diameter in the periumbilical area originating from sigmoid colon cancer in stage IV pT3N1M1 in a 60-year-old female patient
Figure 2
Figure 2
A case of dermoscopy of a skin metastatic nodule from sigmoid colon cancer. This figure presents multiple linear, irregular vessels located centrally and peripherally mimicking stellate telangiectasias as well as dotted vessels, mainly distributed peripherally. The vascular arrangement is irregular. The background is whitish, confluent and homogenous. Partially small, roundish, yellowish dots are observed mimicking the hyperkeratotic plugs which are surrounded by a white halo
Figure 3
Figure 3
Magnification 100×, H + E. In the superficial part of the epidermis, a slight scaling with superficial subcorneal pustules with granulocytic debris was noted. A slight acanthotic proliferation of the epithelium was also found. In the superficial part of the dermis vessels’ proliferation was also observed. In the lumina of the curved and dilated, spirally elongated vessels, well-visible multiple, metastatic carcinomatous emboli were found in the central part of the lesion, where the neovascularization was the most pronounced
Figure 4
Figure 4
Magnification 100×, H + E. In the epidermis, proofis observed of the presence of a dense, inflammatory infiltration, thickened and hyalinizated bundles of collagen and adenocarcinomatous tubules
Figure 5
Figure 5
An example of a macroscopic picture of a metastatic nodule originating from adenocarcinoma of the pancreas. The figure presents a metastatic nodule as non-painful, brownish-pinkish, slightly firm, non-shifting within the skin, sized 2.0 cm in diameter, found on the back of a 61-year-old man
Figure 6
Figure 6
A case of dermoscopy of a skin metastatic nodule from pancreatic cancer. This case presents a dermoscopy of the metastatic skin nodule, which reveals the presence of polymorphous vessels, whose picture remains unclear-mainly irregularly distributed linear straight and irregular, linear serpentine vessels. After the application of slight pressure, the vessels vanished rapidly. The background of the nodule is whitish and structureless, with several brownish-greyish, roundish areas, irregular in shape, similar to peripherally distributed small dots
Figure 7
Figure 7
Magnification 200×, H + E. In the superficial part of the dermis, proliferating, curved, slightly dilated and elongated vessels with metastatic, carcinomatous emboli have been noted. Interstitial fibrosis with hyalinization has also been found
See this image and copyright information in PMC

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