Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015;8 Spec Issue(Spec Issue):21-5.

Plasmatic markers for early diagnostic and treatment decisions in ischemic stroke

D M Stanca  1 , I C Mărginean  1 , O Sorițău  2 , D F Mureșanu  1
Affiliations
Review

Plasmatic markers for early diagnostic and treatment decisions in ischemic stroke

D M Stanca et al. J Med Life. 2015.

Abstract

A neurologic deficit of sudden onset conforming to a vascular territory is a clear clinical indication that a patient suffers from an acute stroke. However, the imagistic diagnostic confirmation is not always readily available. We are now able to offer comprehensive medical support for the patient after an acute stroke and to make a prodigious rehabilitation program after the damage is done, but this is not offering the chance for improvement. An opportunity to better diagnose ischemic stroke seems to be available by using neuronal biomarkers. Extensive research is being conducted in this field and useful information is beginning to gather. This mini-review aims to highlight selected studies that appear to be of particular interest for the clinical neurologist. The most promising biomarkers (or rather panels of biomarkers) are presented with theirs clinical usefulness and limitations.

Keywords: biomarker panel; early diagnosis; ischemic stroke; neuronal biomarker.

PubMed Disclaimer

References

    1. Chalela JA, Kidwell CS, Nentwich LM, et al. Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison. Lancet. 2007;369:293–298. - PMC - PubMed
    1. Whiteley W, Tseng MC, Sandercock P. Blood biomarkers in the diagnosis of ischemic stroke: a systematic review. Stroke. 2008;39:2902–2909. - PubMed
    1. Marginean IC, Stanca DM, Vacaras V, Soritau O, Marginean M, Muresanu DF. Plasmatic markers in hemorrhagic stroke. J Med Life. 2011 May 15;4(2):148–150. - PMC - PubMed
    1. Brouns R, De Deyn PP. The complexity of neurobiological processes in acute ischemic stroket. Clin Neurol Neurosurg. 2009;111:483–495. - PubMed
    1. Saenger KA, Christenson RH. Stroke Biomarkers: Progress and Challenges for Diagnosis, Prognosis, Differentiation, and Treatment. Clinical Chemistry. 2010 Jan;56,1:21–33. - PubMed

Publication types

LinkOut - more resources