[Clinical experience with different modes of preoperative radiotherapy in advanced carcinomas of the tongue and the floor of the mouth]

Abstract

In a controlled prospective study of 90 patients with locally advanced but operable epidermoid carcinomas (T2/T3N0-3M0) of the tongue and the floor of the mouth underwent 3 types of preoperative radiation: 1.5 x 5 Gy; 2.15 x 2 Gy and 3.5 x 2.5 Gy. The preoperative radiation led to a marked decrease of local recidives and to a lengthening of the recidive-free interval respectively. The type of preoperative radiation 5 x 5 Gy seemed to have the most favourable results. Otherwise the preoperative radiation had no advantages in regard to a better prevention of regional metastases and because of that there is no indication for it.