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. 2015 Oct;16(10):561-2.
doi: 10.1038/nrg3998. Epub 2015 Sep 15.

Using human genetics to make new medicines

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Using human genetics to make new medicines

Jeffrey C Barrett et al. Nat Rev Genet. 2015 Oct.

Abstract

Jeffrey Barrett, Ian Dunham and Ewan Birney discuss the initiatives of the newly founded Centre for Therapeutic Target Validation, including a range of approaches to use human genetics to inform drug discovery and make better medicines.

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References

    1. Nature. 2012 Nov 1;491(7422):119-24 - PubMed
    1. Nat Biotechnol. 2014 Jan;32(1):40-51 - PubMed
    1. N Engl J Med. 2015 Mar 19;372(12):1104-13 - PubMed
    1. Nat Genet. 2015 Aug;47(8):856-60 - PubMed
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