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. 2015 Sep 15:14:97.
doi: 10.1186/s12937-015-0086-0.

Effects of kiwi consumption on plasma lipids, fibrinogen and insulin resistance in the context of a normal diet

Jose I Recio-Rodriguez  1   2 , Manuel A Gomez-Marcos  3 , Maria C Patino-Alonso  4 , Elisa Puigdomenech  5 , Blanca Notario-Pacheco  6 , Nere Mendizabal-Gallastegui  7 , Aventina de la Cal de la Fuente  8 , Luis Otegui-Ilarduya  9 , Jose A Maderuelo-Fernandez  3 , Angela de Cabo Laso  3 , Cristina Agudo-Conde  3 , Luis Garcia-Ortiz  3 ; EVIDENT Group
Collaborators, Affiliations

Effects of kiwi consumption on plasma lipids, fibrinogen and insulin resistance in the context of a normal diet

Jose I Recio-Rodriguez et al. Nutr J. .

Abstract

Background and aims: Among fruits, kiwi is one of the richest in vitamins and polyphenols and has strong anti-oxidant effects. We aimed to analyze the relationship between the consumption of kiwi and plasma lipid values, fibrinogen, and insulin resistance in adults within the context of a normal diet and physical-activity.

Methods: Cross-sectional study. Participants (N = 1469), who were free of cardiovascular diseases, completed a visit, which included the collection of information concerning the participant's usual diet and kiwi consumption using a previously validated, semi-quantitative, 137-item food-frequency-questionnaire. Fasting laboratory determinations included plasma lipids, fibrinogen and insulin resistance. Regular physical-activity was determined using accelerometry.

Results: Consumers of at least 1 kiwi/week presented higher plasma values of HDL-cholesterol (mean difference 4.50 [95% CI: 2.63 to 6.36]) and lower triglyceride values (mean difference -20.03 [95% CI: -6.77 to -33.29]), fibrinogen values (mean difference -13.22 [95% CI: -2.18 to -24.26]) and HOMAir values (mean difference -0.30 [95% CI: -0.09 to -0.50]) (p < 0.05, for all comparisons) than those who consumed less than 1 kiwi per week. In an adjusted logistic regression analysis, this group had a lower odds-ratio for presenting plasmatic fibrinogen concentrations above 400 mg/dL (OR = 0.68, 95% CI 0.49 to 0.95), HDL-Cholesterol plasma values below 45 mg/dL (OR = 0.57, 95% CI 0.36 to 0.91) and a HOMAir above 3 (OR = 0.61, 95% CI 0.37 to 1.00).

Conclusions: Consumption of at least one kiwi/week is associated with lower plasma concentrations of fibrinogen and improved plasma lipid profile in the context of a normal diet and regular exercise.

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Figures

Fig. 1
Fig. 1
Fibrinogen, HDL-cholesterol, triglycerides and HOMAir according to kiwi consumption group. The bar graphs represent the marginal means and standard deviations adjusted for age; gender; physical activity (counts/min); total energy intake (kcal); total fruit consumption (gr/week), alcohol consumption (gr/week), body mass index and the presence of lipid-lowering drugs
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References

    1. Hartley L, Igbinedion E, Holmes J, Flowers N, Thorogood M, Clarke A, et al. Increased consumption of fruit and vegetables for the primary prevention of cardiovascular diseases. Cochrane Database Syst Rev. 2013;6:CD009874. - PMC - PubMed
    1. Hertog MG, Feskens EJ, Hollman PC, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet. 1993;342(8878):1007–1011. doi: 10.1016/0140-6736(93)92876-U. - DOI - PubMed
    1. Macready AL, George TW, Chong MF, Alimbetov DS, Jin Y, Vidal A, et al. Flavonoid-rich fruit and vegetables improve microvascular reactivity and inflammatory status in men at risk of cardiovascular disease--FLAVURS: a randomized controlled trial. Am J Clin Nutr. 2014;99(3):479–489. doi: 10.3945/ajcn.113.074237. - DOI - PubMed
    1. Toh JY, Tan VM, Lim PC, Lim ST, Chong MF. Flavonoids from fruit and vegetables: a focus on cardiovascular risk factors. Curr Atheroscler Rep. 2013;15(12):368. doi: 10.1007/s11883-013-0368-y. - DOI - PubMed
    1. Beretz A, Cazenave JP, Anton R. Inhibition of aggregation and secretion of human platelets by quercetin and other flavonoids: structure-activity relationships. Agents Actions. 1982;12(3):382–387. doi: 10.1007/BF01965408. - DOI - PubMed

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